Cell-Based Services

Cell-based assays are complex, require a particular set of expertise, and are an essential part of the development of many new drugs. We offer a comprehensive suite of cell-based assay services, cell-based bioassay services, and cell culture services to expedite your needs.

The Sword Difference

Sword Bio provides custom cell-based solutions from assay development through validation using cell lines or primary cells across various signaling pathways, therapeutic modalities, and disease indications.

We foster true collaboration and actively involve clients in every project phase. Whether the project is designing custom cell-based assays or genomic analysis, Sword Bio delivers comprehensive solutions and data that drive progress in our client's goals against disease. We can support you starting in preclinical through your phase IV studies.

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How Our Team Can Help

  • Mechanism of Action Studies
    • Receptor-Ligand Binding Assay
    • Agonist/antagonist screening
    • Phagocytosis
    • Proliferation/Inhibition Assessment
    • Cell migration and invasion
    • T-Cell Stimulation Cytokine/Chemokine Assessment
  • CMC Lot Release and Stability (Potency) Assessments
    • DNA/RNA impurity Assessments
    • CAR-T and Viral Vector Membrane Protein Lot Release Assessments
  • Cellular Immunogenicity Assessments
    • Immunoassays
    • Cellular Anti-drug antibody (ADA)
    • Lumit™ Immunoassays
    • Neutralizing Antibody (NAb) Assessments
  • Drug Uptake and Target Engagement Assessments
    • Viral Infectivity Assessments
    • Cytotoxicity
    • T-cell activation
    • PBMC stimulation/cell-killing
    • Microglial activation
    • GPCR activation
    • Histone Extraction
  • Flow Cytometry Phenotyping or Signaling Endpoint Assessments
  • Cytotoxicity
    • Complement-dependent cytotoxicity (CDC)
    • Antibody-dependent cellular cytotoxicity (ADCC)